Biostatistics I - 2 units - CLRE-253
Summer
In this course you will gain an understanding of the principles of measurement of clinical data, learn to recognize data types, and to correctly identify statistical methods appropriate for analysis of a given clinical data set. You will gain experience in assembling a clinical dataset in formats suitable for analysis by STATA or other comparable statistical packages. You will also learn skills for conducting graphical and numerical exploratory data analysis, comparative tests of categorical, ordinal, and continuous data, linear and logistic regression analysis, and survival analysis by life table and Kaplan-Meier techniques.
Biostatistics II - 2 units - CLRE-254
Fall
This course gives you the skills to understand and conduct advanced bio-statistical analyses including: multiple linear and logistic regression, survival analysis, and Cox and extended Cox regression. You will become familiar with person-time rate analysis, Poisson regression, and longitudinal data analysis in the presence of missing values and varying measurement times. This course is a pre-requisite for taking advanced stat courses. (You may take an advanced stat course simultaneously with this course.)
Data Management/Informatics - 2 units - CLRE-255
Fall
This course will provide you with an orientation to database design and management, and covers key issues regarding data handling for clinical research and clinical trials. You will also become familiar with technology assessment and decision-making methods and analysis.
Epidemiology I - 2 units - CLRE-251
Summer
This course exposes you to the basic principles of epidemiology, including etiology, transmission, outbreak investigation, disease surveillance, screening, and study design. Students will learn about cross-sectional, case-control, cohort and intervention study designs, their strengths and limitations, and how to make the proper choice of study design for conducting your own research. You will learn to identify and calculate the correct measure of risk for each study design, recognize major sources of bias, confounding and misclassification, and understand design and analysis methods of dealing with each, while becoming familiar with criteria to differentiate association from causation.
Epidemiology II - 2 units - CLRE-257
Fall
This course is designed to introduce you to researchers in various epidemiological content areas, including (but not limited to) spatial, environmental/occupational, cancer, nutrition, tobacco and perinatal/reproductive epidemiology. Students will be exposed to a variety of methodologic considerations, including study design and conduct, measurement issues, bias, and data analysis and interpretation relevant to the unique exposures and outcomes in each content area. Students will gain an understanding of the application of epidemiologic methods, and will be introduced to research possibilities.
Health Services Research - 2 units - CLRE-252
Winter
The main goals of this course are to educate you in identifying the most effective ways to organize, manage, finance, and deliver high quality care; reduce medical errors; and improve patient safety. You will learn about three major aspects of health care: the effectiveness and quality of the care, access to care, and its cost. Data sources and methods (e.g., program evaluation, qualitative research, and survey research) which are used to evaluate the effects and outcomes of the health care system on people’s health will also be introduced in the course.
Patient-Oriented Research I - 2 units - CLRE-250
Summer
In POR I you will learn and apply the basic elements of design, implementation, and analysis of interventional research. You will develop and present a concept proposal for a clinical trial to your peers and the course faculty and submit it as a product of the course.
Patient-Oriented Research II - 2 units - CLRE-256
Fall
POR II builds on POR I by reviewing the ethical and regulatory basis for human research. You will prepare a proposal to the UCSD (institutional Review board (IRB), participate in a mock IRB meeting as both an applicant and reviewer, and submit the completed IRB proposal as the final written submission for the course.
Scientific Communication Skills - 2 units - CLRE-259
Winter
This course covers the key elements of scientific communication skills that are designed to enhance your ability to be a successful clinical researcher. Topics covered in the course include the secrets of making good oral presentations and engaging the audience, learning how to write and prepare abstracts, acquiring the basics of grant writing and submission, and gaining knowledge on how grants are reviewed. The course includes a mock grant study section.
Translational Research Fundamentals - 2 units - CLRE-236
Summer
Students learn principles and practices of translational medicine applied to discovery and development of drugs, devices, and diagnostics. Topics covered include biomarkers, intellectual property, omics, translational imaging, pharmacogenomics-driven treatment, and discovery and development of diagnostics, stem cell therapies, and drugs.
clre@ucsd.edu